Clinical validation of a miniature nuclear probe system for continuous on-line monitoring of cardiac function and ST-segment

Journal Article · Tue Jan 01 00:00:00 EST 1991 · Journal of Nuclear Medicine; (USA)

OSTI ID:6056048

Broadhurst, P; Cashman, P; Crawley, J; Raftery, E; Lahiri, A ^[1]

---

1. Northwick Park Hospital, Harrow, Middlesex (England)

A new, miniature cesium iodide/photodiode nuclear probe (the Cardioscint) has been developed for continuous on-line measurement of left ventricular function and the ST-segment. Ejection fraction (EF) measurements in 77 patients were compared with gated equilibrium radionuclide ventriculograms. The probe was positioned over the left ventricle by first using a blind positioning algorithm and then by using the gamma camera. Background was measured both manually and automatically. There was good correlation between probe (positioned blind) and gamma camera EF with both manual (r = 0.80, n = 65) and automatic (r = 0.78, n = 66) backgrounds. Use of the gamma camera did not significantly alter the results. Correlation between the probe stroke counts and thermodilution-derived stroke index during atrial pacing in six subjects was also satisfactory (r = 0.69, n = 102). Thus, the Cardioscint is able to provide a reliable estimate of EF and can track rapid changes in cardiac volumes.

• OSTI ID: 6056048
• Journal Information: Journal of Nuclear Medicine; (USA), Vol. 32:1; ISSN 0161-5505
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CARDIOVASCULAR DISEASES
DIAGNOSIS
HEART
DYNAMIC FUNCTION STUDIES
ALGORITHMS
CESIUM ISOTOPES
GAMMA CAMERAS
RADIOISOTOPE SCANNING
SCINTILLATION COUNTING
ALKALI METAL ISOTOPES
BODY
CAMERAS
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DISEASES
ISOTOPES
MATHEMATICAL LOGIC
ORGANS
550601* - Medicine- Unsealed Radionuclides in Diagnostics