X-ray microanalysis of psoriatic skin

Journal Article · Tue Oct 01 00:00:00 EDT 1985 · J. Invest. Dermatol.; (United States)

DOI:https://doi.org/10.1111/1523-1747.ep12277009· OSTI ID:6042398

Grundin, T G; Roomans, G M; Forslind, B; Lindberg, M; Werner, Y

Electron probe x-ray microanalysis was used to study elemental distribution in uninvolved and involved skin from patients with psoriasis, and in skin from healthy controls. Significant differences were found between the involved and uninvolved psoriatic skin. In the involved skin, the concentrations of Mg, P, and K were higher in the stratum germinativum, spinosum, and granulosum, compared to the corresponding strata in uninvolved skin. Neither involved nor uninvolved psoriatic stratum germinativum differed markedly from nonpsoriatic control stratum germinativum. In uninvolved psoriatic skin only a lower level of K was noted. In comparison to uninvolved psoriatic skin, the elemental composition of the various strata of involved psoriatic skin shows a pattern typical for highly proliferative, nonneoplastic cells.

• Research Organization: Univ. of Stockholm, Sweden
• OSTI ID: 6042398
• Journal Information: J. Invest. Dermatol.; (United States), Journal Name: J. Invest. Dermatol.; (United States) Vol. 4; ISSN JIDEA
• Country of Publication: United States
• Language: English

Related Subjects

550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ALKALI METALS
ALKALINE EARTH METALS
BODY
CALCIUM
CHEMICAL ANALYSIS
CHLORINE
DISEASES
ELEMENTS
HALOGENS
MAGNESIUM
METALS
MICROANALYSIS
NONDESTRUCTIVE ANALYSIS
NONMETALS
ORGANS
PATHOLOGY
PATIENTS
PHOSPHORUS
POTASSIUM
PSORIASIS
SKIN
SKIN DISEASES
SODIUM
SULFUR
X-RAY EMISSION ANALYSIS