Radiation management of carcinoma of the cervical stump. [Complications following external and internal radiotherapy]

Conference · Sun Apr 01 04:00:00 EST 1979 · Cancer; (United States)

OSTI ID:6036918

Prempree, T; Patanaphan, V; Scott, R M

In spite of a low incidence of carcinoma of the cervical stump at the present time, the management of this interesting disease deserves special attention because of the success which can be obtained with proper treatment. Of 107 cases treated, only 100 cases were true cases of carcinoma of the stump and were eligible for this study. 7 cases were excluded from the study because they were probably coincidental carcinomas and were treated soon after subtotal hysterectomy. The lesions were staged according to the FIGO system. 93 cases were invasive squamous cell carcinoma, 6 cases adenocarcinoma and 1 case transitional cell carcinoma. Of 100 cases with a minimum 5 year follow-up, the absolute 5-year cure rate for various clinical stages is as follows: State I 83.3% (20/24); Stage IIA 75.0% (9/12); Stage IIB 62.5% (20/32); Stage IIIA 50% (1/2); Stage IIIB 48% (12/25); Stage IV 20% (1/5). The overall absolute 5-year cure rate for all stages combined is 63%. A better result in Stage IIIB as compared to several previous reports is thought to be due to extensive and aggressive interstitial radium therapy properly combined with external supervoltage irradiation. Techniques of treatment stage by stage including computerized dosimetry are discussed along with complications and failures.

• Research Organization: Univ. of Maryland Hospital, Baltimore
• OSTI ID: 6036918
• Conference Information: Journal Name: Cancer; (United States) Journal Volume: 43:4
• Country of Publication: United States
• Language: English

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560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACCELERATORS
ALKALINE EARTH METALS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETATRONS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BLADDER
BODY
BODY AREAS
CARCINOMAS
COBALT 60
COBALT ISOTOPES
CYCLIC ACCELERATORS
DELAYED RADIATION EFFECTS
DIGESTIVE SYSTEM
DISEASES
ELECTROMAGNETIC RADIATION
ELEMENTS
EXTERNAL IRRADIATION
FEMALE GENITALS
FEMALES
FISTULAE
FRACTIONATED IRRADIATION
GAMMA RADIATION
GASTROINTESTINAL TRACT
IMPLANTS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
INTERNAL IRRADIATION
INTESTINES
IONIZING RADIATIONS
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LARGE INTESTINE
LINEAR ACCELERATORS
MAMMALS
MAN
MEDICINE
METALS
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PARTIAL BODY IRRADIATION
PATHOLOGICAL CHANGES
PATIENTS
PELVIS
PRIMATES
RADIATION EFFECTS
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIATIONS
RADIOINDUCTION
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
RADIUM
RECTUM
SIDE EFFECTS
THERAPY
URINARY TRACT
UTERUS
VERTEBRATES
WOMEN
X RADIATION
YEARS LIVING RADIOISOTOPES