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Bone healing in rabbits after compression osteosynthesis, studied by Tc-99m(Sn)polyphosphate scintimetry and autoradiography

Journal Article · · J. Nucl. Med.; (United States)
OSTI ID:6036912
The purpose of the present study was to determine the scintimetric time course (STC) for Tc-99m(Sn)polyphosphate in rabbit tibias after various osteosynthetic procedures, and to correlate the findings with those from serial radiographs and with autoradiographic and histologic evaluation of the bone. The STC was similar for all treatment groups, with a peak value within the second week after surgery. The radiological, autoradiographic, and histological findings revealed that Tc-99m scintimetry monitors callus formation. The STC thus appears to be a valuable tool for the quantitative study of bone healing.
Research Organization:
Univ. of Copenhagen, Denmark
OSTI ID:
6036912
Journal Information:
J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 22:8; ISSN JNMEA
Country of Publication:
United States
Language:
English