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Tautomerism in the series of acetylpinacolin acylhydrazones

Journal Article · · J. Org. Chem. USSR (Engl. Transl.); (United States)
OSTI ID:6035614

It was shown by PMR spectroscopy that acetylpinacolin acylhydrazones exist in deuterochloroform and deuterodimethyl sulfoxide solutions as mixtures of the hydrazone, enehydrazine, and cyclic 5-hydroxypyrazoline forms. In the series of acetylpinacolin aroylhydrazones the introduction of electron-withdrawing substituents into the aromatic ring of the N-aroyl radical shifts the ring-chain tautomeric equilibrium toward the 5-hydroxypyrazoline form. In the series of products from the condensation of acetylpinacolin with the hydrazides of aliphatic acids the proportion of the open-chain tautomer increases with increase in the size of substituent in the N-acyl part.

Research Organization:
A.A. Zhdanov Leningrad State Univ., USSR
OSTI ID:
6035614
Journal Information:
J. Org. Chem. USSR (Engl. Transl.); (United States), Journal Name: J. Org. Chem. USSR (Engl. Transl.); (United States) Vol. 21:12; ISSN JOCYA
Country of Publication:
United States
Language:
English

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