High-risk angina patient: identification by clinical features, hospital course, electrocardiography, and technetium-99m stannous pyrophosphate scintigraphy

Journal Article · Thu Oct 01 00:00:00 EDT 1981 · Circulation; (United States)

DOI:https://doi.org/10.1161/01.CIR.64.4.674· OSTI ID:6028486

Olson, H G ^[1]; Lyons, K P; Aronow, W S; Stinson, P J; Kuperus, J; Waters, H J

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1. Univ. of California, Irvine

We evaluated 193 consecutive unstable angina patients by clinical features, hospital course and electrocardiography. All patients were managed medically. Of the 193 patients, 150 (78%) had a technetium-99m pyrophosphate (Tc-PYP) myocardial scintigram after hospitalization. Of these, 49 (33%) had positive scintigrams. At a follow-up of 24.9 +- 10.8 months after hospitalization, 16 of 49 patients (33%) with positive scintigrams died from cardiac causes, compared with six of 101 patients (6%) with negative scintigrams (p < 0.001). Of 49 patients with positive scintigrams, 11 (22%) had had nonfatal myocardial infarction at follow-up, compared with seven of 101 patients (7%) with negative scintigrams (p < 0.01). Age, duration of clinical coronary artery disease, continuing angina during hospitalization, ischemic ECG, cardiomegaly and a history of heart failure also correlated with cardiac death at follow-up. Ischemic ECG and a history of angina with a crescendo pattern also correlated with nonfatal infarction at follow-up. Patients with continuing angina, an ischemic ECG and a positive scintigram constituted a high-risk unstable angina subgroup, with a survival rate of 58% at 6 months, 47% at 12 months and 42% at 24 and 36 months. We conclude that the assessment of clinical features, hospital course, ECG and Tc-PYP scintigraphy may be useful in identifying high-risk unstable angina patients.

• OSTI ID: 6028486
• Journal Information: Circulation; (United States), Journal Name: Circulation; (United States) Vol. 64:4; ISSN CIRCA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DATA
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
EVALUATED DATA
EVALUATION
HAZARDS
HEART
INFORMATION
ISOMERIC NUCLEI
MORTALITY
MUSCLES
MYOCARDIUM
NUCLEI
NUMERICAL DATA
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
SCINTISCANNING
STATISTICAL DATA
SURVIVAL CURVES
TECHNETIUM COMPOUNDS
TRANSITION ELEMENT COMPOUNDS
UPTAKE