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Alkylation of CH acids in the presence of potassium carbonate. III. Alkylation of CH acids by 2,3-substituted 1,4-dibromo-2-butenes

Journal Article · · J. Org. Chem. USSR (Engl. Transl.); (United States)
OSTI ID:6008994

During the cycloalkylation of CH acids by 2,3-substituted (methyl-chlorine) 1,4-dibromo-2-butenes the direction of intramolecular C- and O-alkylation depends both on steric and on electronic factors. The introduction of substituents into the alkylating agent and the presence of acetyl groups in the initial CH acids promote regiospecific intramolecular O-alkylation. It was found that the initial alkylation of the enolizing CH acids with 1,4-dibromo-2-methyl-2-butene in the presence of potassium carbonate takes place with high regioselectivity at the unsubstituted end of the butene chain.

Research Organization:
All-Union Scientific-Research Institute, IREA, Erevan (USSR)
OSTI ID:
6008994
Journal Information:
J. Org. Chem. USSR (Engl. Transl.); (United States), Journal Name: J. Org. Chem. USSR (Engl. Transl.); (United States) Vol. 24:7; ISSN JOCYA
Country of Publication:
United States
Language:
English

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