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An Optimized Epithermal Neutron Beam for Neutron Capture Therapy (NCT) at the Brookhaven Medical Research Reactor (BMRR)

Conference · · Progress in Neutron Capture Therapy for Cancer
 [1];  [2];  [3];  [1];  [4];  [4];  [5];  [5];  [6];  [7];  [7];  [7];  [1];  [1]
  1. Brookhaven National Laboratory (BNL), Upton, NY (United States)
  2. Brookhaven National Laboratory (BNL), Upton, NY (United States); Tel Aviv Univ. (Israel)
  3. Brookhaven National Laboratory (BNL), Upton, NY (United States); Univ. of Ioannina (Greece)
  4. Univ. of Missouri, Columbia, MO (United States)
  5. The Ohio State Univ., Columbus, OH (United States)
  6. Brookhaven National Laboratory (BNL), Upton, NY (United States); State Univ. of New York (SUNY), Stony Brook, NY (United States)
  7. State Univ. of New York (SUNY), Stony Brook, NY (United States)
The first clinical trials of NCT were initiated at Brookhaven in 1951, using the Brookhaven Graphite Research Reactor (BGRR). Subsequently, the Brookhaven Medical Research Reactor (BMRR) was built primarily for clinical applications of NCT, with an improved beam extraction facility providing flexibility for future development of filters/moderators for NCT. This flexibility was exploited to provide an optimized epithermal neutron beam which was recently installed and tested in the east irradiation facility (shutter) of the BMRR.
Research Organization:
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Organization:
USDOE; National Institutes of Health (NIH)
DOE Contract Number:
AC02-76CH00016
OSTI ID:
6007950
Report Number(s):
BNL--45809; CONF-901226--1; ON: DE91009470; ISBN: 978-0-306-44104-2
Conference Information:
Journal Name: Progress in Neutron Capture Therapy for Cancer
Country of Publication:
United States
Language:
English

References (5)

The Relative Biological Effectiveness in V79 Chinese Hamster Cells of the Neutron Capture Reactions in Boron and Nitrogen journal May 1984
Comparison of measured parameters from a 24–keV and a broad spectrum epithermal neutron beam for neutron capture therapy: An identification of consequential parameters journal November 1990
The effect of geometry on capillary wall dose for boron neutron capture therapy journal January 1976
The Monte Carlo Simulation of the Biological Effect of the 10 B(n,α) 7 Li Reaction in Cells and Tissue and Its Implication for Boron Neutron Capture Therapy journal July 1987
Installation and Testing of an Optimized Epithermal Neutron Beam at the Brookhaven Medical Research Reactor (BMRR) book January 1990

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