Ozonolysis of substituted uracils

Journal Article · Fri Feb 16 04:00:00 EST 1990 · Journal of Organic Chemistry; (United States)

DOI:https://doi.org/10.1021/jo00291a062· OSTI ID:6004814

Matsui, Masaki; Kamiya, Kazusaki; Shibata, Katsuyoshi; Muramatsu, Hiroshige ^[1]

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1. Gifu Univ. (Japan)

The reactions of cellular substances with ozone is one of the most important subjects in ozone chemistry. Although the ozonization reactions of DNA and RNA are of interest in connection with damage to biological systems, these reactions have received only limited attention. With pyrimidine nucleotides, ozone preferentially attacks the base moieties. Recently, the ozonolysis of uracils to give 1-acyl-5-hydroxyhydantoins has been reported. In order to obtain new substituted 1-acyl-5-hydroxyhydantoins, substituent effects on the ozonolysis of uracils were examined.

• OSTI ID: 6004814
• Journal Information: Journal of Organic Chemistry; (United States), Journal Name: Journal of Organic Chemistry; (United States) Vol. 55:4; ISSN 0022-3263; ISSN JOCEA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400201 -- Chemical & Physicochemical Properties
54 ENVIRONMENTAL SCIENCES
540120* -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (1990-)
AZINES
AZOLES
CHEMICAL PREPARATION
CHEMICAL REACTION KINETICS
CHEMICAL REACTIONS
HETEROCYCLIC COMPOUNDS
HYDANTOINS
HYDROXY COMPOUNDS
IMIDAZOLES
KINETICS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
OZONIZATION
PYRIMIDINES
REACTION KINETICS
SYNTHESIS
URACILS