Enzymes and isoenzymes in pathogenesis and diagnosis
Book
·
OSTI ID:5995532
This book, based on 19 review articles discusses how enzymes and isoenzymes can be used in diagnosis, and the role they play in the pathogenesis of disease. The opening reports concentrate on the digestive system. Topics covered are advances in the diagnostic use of alkaline phosphatase isoenzymes, enzymes of value in pancreatic disease, and the modulation by steroids of gamma-glutamyltransferase in fetal hepatocytes. Advances are described such as the multiplicity of enzyme defects at the root of common inherited metabolic diseases. Newer applications of enzymology are shown, as in the role of purine-related enzymes in leukemia and immunodeficiency states. The role of enzymes in metabolic abnormalities such as oxylate formation, disorders of peroxisomal metabolism, hyperphenylalaninemia, and methemoglobinemia is explored.
- OSTI ID:
- 5995532
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550200 -- Biochemistry
550600* -- Medicine
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ALKALINE PHOSPHATASE
BIOASSAY
BIOLOGICAL MARKERS
BIOLOGY
BODY
DIAGNOSIS
DIAGNOSTIC USES
DIGESTIVE SYSTEM
DISEASES
ENDOCRINE GLANDS
ENZYMES
ESTERASES
ETIOLOGY
GENETICS
GLANDS
HEMIC DISEASES
HEREDITARY DISEASES
HYDROLASES
ISOENZYMES
LEUKEMIA
LIVER
METABOLIC DISEASES
METABOLISM
NEOPLASMS
ORGANS
PANCREAS
PATHOGENESIS
PHOSPHATASES
STRUCTURE-ACTIVITY RELATIONSHIPS
TRANSFERASES
USES
550600* -- Medicine
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ALKALINE PHOSPHATASE
BIOASSAY
BIOLOGICAL MARKERS
BIOLOGY
BODY
DIAGNOSIS
DIAGNOSTIC USES
DIGESTIVE SYSTEM
DISEASES
ENDOCRINE GLANDS
ENZYMES
ESTERASES
ETIOLOGY
GENETICS
GLANDS
HEMIC DISEASES
HEREDITARY DISEASES
HYDROLASES
ISOENZYMES
LEUKEMIA
LIVER
METABOLIC DISEASES
METABOLISM
NEOPLASMS
ORGANS
PANCREAS
PATHOGENESIS
PHOSPHATASES
STRUCTURE-ACTIVITY RELATIONSHIPS
TRANSFERASES
USES