Bone marrow ablation followed by allogeneic marrow grafting during first complete remission of acute nonlymphocytic leukemia

Journal Article · Mon Feb 28 23:00:00 EST 1983 · Blood; (United States)

OSTI ID:5995347

Forman, S J; Spruce, W E; Farbstein, M J

Of 33 patients who had undergone allogeneic bone marrow transplantation during first complete remission of acute nonlymphocytic leukemia, 21 patients have now been followed in continued complete remission for 6-64 mo (median greater than 18 mo) without maintenance chemotherapy. The median age of the surviving patients is 27 yr. Transplant-related complications occurring throughout the first year after marrow grafting were fatal in 7 patients, and leukemic recurrence led to the death of 5 patients. The actuarial long-term disease-free survival is 60% and the actuarial remission rate is 79%.

• Research Organization: Department of Hematology and BMT, City of Hope National Medical Center, Duarte, CA
• OSTI ID: 5995347
• Journal Information: Blood; (United States), Journal Name: Blood; (United States) Vol. 61:3; ISSN BLOOA
• Country of Publication: United States
• Language: English

Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
560151 -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMAL TISSUES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BONE MARROW
BONE MARROW CELLS
CHEMOTHERAPY
CONNECTIVE TISSUE CELLS
DISEASES
EXTERNAL IRRADIATION
HEMATOPOIETIC SYSTEM
HEMIC DISEASES
IRRADIATION
LEUKEMIA
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIATION EFFECTS
RADIOLOGY
RADIOTHERAPY
SOMATIC CELLS
SURVIVAL TIME
THERAPY
TISSUES
TRANSPLANTS
WHOLE-BODY IRRADIATION