Nuclear medicine studies in evaluation of skeletal lesions in children with histiocytosis X/sup 1/

Conference · Tue Sep 01 04:00:00 EDT 1981 · Radiology; (United States)

OSTI ID:5995325

Siddiqui, A R; Tashjian, J H; Lazarus, K; Wellman, H N; Baehner, R L

Radiographs were compared with /sup 99m/Tc scans of the bones and bone marrow as well as /sup 67/Ga-citrate scans to evaluate their sensitivity in identifying skeletal lesions in 21 children with histiocytosis X. Seven of 20 bone scans were completely normal in patients with extensive radiographic evidence of skeletal disease. In only one patient were bone scan changes demonstrated prior to radiographic abnormalities. None of the lesions was cold on the bone scans. /sup 99m/Tc-sulfur colloid bone marrow scans and /sup 67/Ga-citrate whole-body scans were not valuable. Radiographic survey of the skeleton should be the primary diagnostic test employed in patients with histiocytosis X who have suspected skeletal lesions. Bone scans should be obtained only when the radiographs are normal or equivocal.

• OSTI ID: 5995325
• Conference Information: Journal Name: Radiology; (United States) Journal Volume: 140:3
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AGE GROUPS
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOMEDICAL RADIOGRAPHY
BODY
BONE MARROW
CARBOXYLIC ACID SALTS
CHILDREN
CITRATES
COLLOIDS
COMPARATIVE EVALUATIONS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISPERSIONS
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
ESTERS
GALLIUM 67
GALLIUM ISOTOPES
HEMATOPOIETIC SYSTEM
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
PHOSPHORIC ACID ESTERS
RADIOCOLLOIDS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY
RADIOPHARMACEUTICALS
RETICULOENDOTHELIAL SYSTEM
SCINTISCANNING
SKELETON
TECHNETIUM 99
TECHNETIUM ISOTOPES
TISSUES
YEARS LIVING RADIOISOTOPES