The investigation of radiopharmaceutical components by fast atom bombardment mass spectrometry: the identification of Tc-HIDA and the epimers of Tc-CO2DADS
Journal Article
·
· J. Nucl. Med.; (United States)
OSTI ID:5994785
The nature of two technetium-labeled radiopharmaceutical components has been established by means of fast-atom-bombardment mass spectrometry (FABMS) in combination with carrier-added (CA) and no-carrier-added (NCA) reversed-phase high-pressure liquid chromatography (HPLC). Negative-ion FABMS was used to determine that the epimers of Tc-CO2DADS are the oxo(N,N'-(1-carboxyethylene)-bis-(2-mercaptoacetimido))technetate(V) ions; positive-ion FABMS showed that Tc-HIDA is bis(N-(2,6-dimethylphenyl-carbamoylmethyliminodiaceto)technetate(III).
- Research Organization:
- Massachusetts Institute of Technology, Cambridge
- OSTI ID:
- 5994785
- Journal Information:
- J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 24:4; ISSN JNMEA
- Country of Publication:
- United States
- Language:
- English
Similar Records
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Sat Mar 31 23:00:00 EST 1979
· J. Nucl. Med.; (United States)
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OSTI ID:6295642
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Sat Oct 01 00:00:00 EDT 1977
· J. Nucl. Med.; (United States)
·
OSTI ID:5372353
Charge and nature of technetium species produced in the reduction of pertechnetate by stannous ion. [/sup 99m/Tc]
Journal Article
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Mon Oct 31 23:00:00 EST 1977
· J. Nucl. Med.; (United States)
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OSTI ID:5304935
Related Subjects
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
400702* -- Radiochemistry & Nuclear Chemistry-- Properties of Radioactive Materials
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CHROMATOGRAPHY
DRUGS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LIQUID COLUMN CHROMATOGRAPHY
MASS SPECTROSCOPY
NUCLEI
ODD-EVEN NUCLEI
OXYGEN COMPOUNDS
RADIOISOTOPES
RADIOPHARMACEUTICALS
SEPARATION PROCESSES
SPECTROSCOPY
STRUCTURAL CHEMICAL ANALYSIS
TECHNETATES
TECHNETIUM 99
TECHNETIUM COMPOUNDS
TECHNETIUM ISOTOPES
TRANSITION ELEMENT COMPOUNDS
YEARS LIVING RADIOISOTOPES
400702* -- Radiochemistry & Nuclear Chemistry-- Properties of Radioactive Materials
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CHROMATOGRAPHY
DRUGS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LIQUID COLUMN CHROMATOGRAPHY
MASS SPECTROSCOPY
NUCLEI
ODD-EVEN NUCLEI
OXYGEN COMPOUNDS
RADIOISOTOPES
RADIOPHARMACEUTICALS
SEPARATION PROCESSES
SPECTROSCOPY
STRUCTURAL CHEMICAL ANALYSIS
TECHNETATES
TECHNETIUM 99
TECHNETIUM COMPOUNDS
TECHNETIUM ISOTOPES
TRANSITION ELEMENT COMPOUNDS
YEARS LIVING RADIOISOTOPES