Visual cell profiles for quantitation of premalignant cells in sputum: a preliminary report
Journal Article
·
· Acta Cytol.; (United States)
OSTI ID:5990642
Visual cell profiles were used to analyze the distribution of atypical bronchial cells in sputum specimens from cigarette-smoking volunteers, cigarette-smoking asbestos workers and cigarette-smoking uranium miners. The preliminary results of these sputum visual cell profile studies have demonstrated distinctive distributions of bronchial cell atypias in progressive patterns of squamous metaplasia, mild, moderate and severe atypias and carcinoma, similar to those the authors have previously reported using cell image analysis techniques to determine an atypia status index (ASI). The information gained from this study will be helpful in further validating this ASI and subsequently achieving the ultimate goal of employing cell image analysis for the rapid and precise identification of premalignant atypias in sputum.
- Research Organization:
- Department of Pathology, Baylor College of Medicine, Houston, Texas
- OSTI ID:
- 5990642
- Journal Information:
- Acta Cytol.; (United States), Journal Name: Acta Cytol.; (United States) Vol. 26:6; ISSN ACYTA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AEROSOLS
ASBESTOS
BIOLOGICAL MATERIALS
BIOLOGY
BODY FLUIDS
BRONCHI
CARCINOMAS
COLLOIDS
CYTOLOGY
DIAGNOSTIC TECHNIQUES
DISEASES
DISPERSIONS
HAZARDS
HEALTH HAZARDS
MATERIALS
MINERS
MINES
NEOPLASMS
PERSONNEL
RESIDUES
RESPIRATORY SYSTEM
RESPIRATORY SYSTEM DISEASES
SMOKES
SOLS
TOBACCO SMOKES
UNDERGROUND FACILITIES
URANIUM MINES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AEROSOLS
ASBESTOS
BIOLOGICAL MATERIALS
BIOLOGY
BODY FLUIDS
BRONCHI
CARCINOMAS
COLLOIDS
CYTOLOGY
DIAGNOSTIC TECHNIQUES
DISEASES
DISPERSIONS
HAZARDS
HEALTH HAZARDS
MATERIALS
MINERS
MINES
NEOPLASMS
PERSONNEL
RESIDUES
RESPIRATORY SYSTEM
RESPIRATORY SYSTEM DISEASES
SMOKES
SOLS
TOBACCO SMOKES
UNDERGROUND FACILITIES
URANIUM MINES