Bioorganometallic chemistry. 2. Synthesis and structural studies of the reactions of a nucleobase, 1-methylcytosine, with a ([eta][sup 5]-pentamethylcyclopentadienyl)rhodium aqua complex
- Lawrence Berkeley Lab., CA (United States)
- Univ. of California, Davis (United States)
The reactions of a nucleobase, 1-methylcytosine (MC), with a Cp*Rh aqua complex, [([eta][sup 5]-Cp*)Rh(H[sub 2]O)[sub 2](OTf)[sub 2]][sub x] (2), provided two different complexes depending on the solvent media. Complex 3, [([eta][sup 5]-Cp*)Rh([eta][sup 1](N3)-MC)([eta][sup 2](O2,N3)-MC)](OTf) [sub 2], was formed when acetone was used as the solvent; however, when complex 3 was recrystallized from water (pH 5.1) or when water was used as the reaction solvent, complex 4, trans-[([eta][sup 5]Cp*)Rh([eta][sup 1](N3)-MC)([mu]-OH)][sub 2](OTf)[sub 2], was isolated as a crystalline solid. The structures of 3 and 4 were verified by [sup 1]H NMR, FAB/MS, elemental analysis, and single-crystal X-ray analysis. The structure of complex 3 showed one MC ligand bound via N3 and the other chelated via N3 and C=02 (Rh-02 = 2.251(6) [angstrom]). Inspection of several bond lengths of complex 4 indicates extensive intramolecular hydrogen bonding of the [mu]-OH groups with the exocyclic NH[sub 2](HO---HNH = 1.93(1) [angstrom]) and the 2-C=O group (OH---O=C = 1.96(1) [angstrom]). 13 refs., 2 figs.
- DOE Contract Number:
- AC03-76SF00098
- OSTI ID:
- 5989348
- Journal Information:
- Organometallics; (United States), Journal Name: Organometallics; (United States) Vol. 12:3; ISSN 0276-7333; ISSN ORGND7
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
ACETONE
CHEMICAL REACTIONS
COMPLEXES
CRYSTALLIZATION
HYDROGEN COMPOUNDS
KETONES
LIGANDS
MAGNETIC RESONANCE
MOLECULAR STRUCTURE
NUCLEAR MAGNETIC RESONANCE
ORGANIC COMPOUNDS
ORGANOMETALLIC COMPOUNDS
OXYGEN COMPOUNDS
PHASE TRANSFORMATIONS
RESONANCE
RHODIUM COMPLEXES
TRANSITION ELEMENT COMPLEXES
WATER