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Biosolubilization of coal by a genetically characterized fungus

Thesis/Dissertation ·
OSTI ID:5986551

Biosolubilization of lignite at ambient temperatures and pressure by the genetically well characterized fungus Neurospora crassa is reported. The fungus also demonstrates the ability to survive on media containing solubilized coal compounds as the sole carbon source. An extracellular protein with an apparent molecular weight of approximately 84,000 daltons that functions in the biosolubilizations process has been isolated and purified to apparent homogeneity. Enhanced secretions of this protein can be induced by the treatment of the growing culture with the protein synthesis inhibitor cycloheximide. Characterization of the heat stability of the solubilizing agent led to the discovery of another, more heat stable, putative solubilization factor having a molecular weight of less than 10,000 daltons. This factor is remarkably similar to a factor that has been previously discovered in another microbial system. Several sources of non-biological solubilization activity were discovered and examined, as well as finding that a common extracellular enzyme, laccase, has the apparent ability to heighten the degree of biosolubilization brought about by the purified solubilizing factor. The amino acid composition of the biologically active protein was determined and found to be distinct from that of laccase. Finally, electrophoretic separation of the products of solubilized lignite indicate a possible difference in breakdown products between coal treated with different chemical and biological agents.

Research Organization:
South Carolina Univ., Columbia, SC (United States)
OSTI ID:
5986551
Country of Publication:
United States
Language:
English