Computed tomographic study of hormone-secreting microadenomas
A review was made of the computed tomographic (CT) studies of 33 patients with hormone-secreting microadenomas that had been verified by transsphenoidal surgery and endocrinologic evaluation. In previous studies in small series of patients, the CT appearance of pituitary microadenomas has been reported as hypodense, isodense, and hyperdense. In this study, CT showed a region of diminished enhancement and ususally an enlarged pituitary gland in cases of prolactin-secreting adenomas. HGH- or ACTH-secreting adenomas were less consistently hypodense. It is concluded that hypodensity and enlargement in the pituitary gland are the most useful criteria for identification of microadenomas. Some technical factors that may affect the CT appearance of microadenomas and lead to conflicting reports are discussed.
- Research Organization:
- Froedtert Memorial Lutheran Hospital, Milwaukee, WI
- OSTI ID:
- 5986253
- Journal Information:
- Radiology; (United States), Journal Name: Radiology; (United States) Vol. 146:1; ISSN RADLA
- Country of Publication:
- United States
- Language:
- English
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62 RADIOLOGY AND NUCLEAR MEDICINE
ACTH
ADENOMAS
BODY
CLASSIFICATION
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ENDOCRINE GLANDS
GLANDS
GONADOTROPINS
HORMONES
LTH
NEOPLASMS
ORGANS
PATIENTS
PEPTIDE HORMONES
PITUITARY GLAND
PITUITARY HORMONES
STH
TOMOGRAPHY