Sensitivity (SENS), specificity (SPEC) and predictive value (PV) of CCK cholescintigraphy: Follow-up of 99 surgically proven cases

Conference · Wed May 01 04:00:00 EDT 1985 · J. Nucl. Med.; (United States)

OSTI ID:5975710

Fink-Bennett, D; DeRidder, P; Kolozsi, W; Gordon, R

To determine the SENS, SPEC and PV of CCK chole-scintigraphy (C) in the detection of acalculous biliary disease (ABD), the authors retrospectively evaluated the gallbladder ejection fraction response (GBEFR) to CCK in 99 post-cholecystectomy (Cx) patients (pts.) with pathologically proven ABD. The path criteria for chronic acalculous cholecystitis and/or the cystic duct syndrome included hypertrophy of the gallbladder wall (>1.5-2mm), diffuse hypertrophy of the muscularis propria with or without a concomitant mononuclear infiltration, serosal thickening, Aschoff-Rokitansky sinuses, foamy macrophages filling the tips of mucosal folds, yellow papillary nodule(s), fibrosis of the cystic duct, kinking or adhesions of the cystic duct seen at operation. The GBEFR to CCK indicative of ABD was defined as one in which the GBEFR was <35%. CCK C was performed after an overnight fast. Each pt. received 5 mCi of technetium-99m Hepatolite. When the GB maximally filled, .02 ..mu..g/kg CCK was administered (1-3 min.) I.V. Background corrected GBEFs were determined q.5 min. X4 by ratioing the pre-CCK GB cts minus post-CCK GB cts. to pre-CCK GB cts. The results of this clinical study are presented in this paper.

• Research Organization: William Beaumont Hospital, Royal Oak, MI
• OSTI ID: 5975710
• Report Number(s): CONF-850611-
• Conference Information: Journal Name: J. Nucl. Med.; (United States) Journal Volume: 26:5
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
550602 -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BILIARY TRACT
BIOMEDICAL RADIOGRAPHY
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DIGESTIVE SYSTEM DISEASES
DISEASES
MEDICINE
NUCLEAR MEDICINE
PAIN
PATIENTS
RADIOISOTOPE SCANNING
RADIOLOGY
RELIABILITY
SCINTISCANNING
SENSITIVITY
SYMPTOMS