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Five-membered 2,3-dioxoheterocycles. VI. Effect of solvation on the kinetics of ring opening in 5-aryl-2,3-dihydrofuran-2,3-diones by the action of aniline

Journal Article · · J. Org. Chem. USSR (Engl. Transl.); (United States)
OSTI ID:5971300
The noncatalytic reactions of 5(4-ethoxyphenyl)-2,3-dihydrofuran-2,3-dione with aniline in cyclohexane, chlorobenzene, nitrobenzene, and their mixtures and the reactions catalyzed by benzoic acid were studied by spectrophotometry at 25/degree/C. The kinetic data, treated by means of the Kirkwood equation, indicate preferred transformation of the nonpolar tetrahedral intermediate product of the noncatalytic reaction into p-ethoxybenzoylpyruvanilide through a five-membered transition state.
Research Organization:
Perm Pharmaceutical Institute (USSR)
OSTI ID:
5971300
Journal Information:
J. Org. Chem. USSR (Engl. Transl.); (United States), Journal Name: J. Org. Chem. USSR (Engl. Transl.); (United States) Vol. 24:2; ISSN JOCYA
Country of Publication:
United States
Language:
English

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