Aspiration biopsy of testis: another method for histologic examination

Conference · Wed Aug 01 04:00:00 EDT 1984 · Fert. Steril.; (United States)

OSTI ID:5962935

Nseyo, U O; Englander, L S; Huben, R P; Pontes, J E

The most important method for evaluating the pathogenesis of male infertility is open testicular biopsy. Herein the authors describe a method of aspiration biopsy of testis for histologic examination. Sexually mature dogs and rats treated with chemotherapeutic agents and ionizing radiation were followed with periodic testicular aspiration biopsy during and after treatment. The histologic findings from the aspiration biopsy compare with the results of routine histologic examination in assessing spermatogenetic activity and delineating pathologic changes. The puncture in the experimental animals was performed under general anesthesia. In human patients testicular biopsy could be done under local anesthesia in an outpatient clinic. The procedure would be less painful, minimally invasive, and more cost-effective.

• Research Organization: Roswell Park Memorial Institute, Buffalo, NY
• OSTI ID: 5962935
• Conference Information: Journal Name: Fert. Steril.; (United States) Journal Volume: 42:2
• Country of Publication: United States
• Language: English

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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
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REPRODUCTIVE DISORDERS
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