Left ventricular performance in type-II diabetics with first acute myocardial infarction: A radionuclide assessment
To assess myocardial performance in diabetics following acute myocardial infarction (AMI), resting gated radionuclide studies with Tc-99m were performed within two weeks of the onset of symptoms in matched groups of 18 type-II diabetics with their first clinical AMI (D-AMI), 20 nondiabetics with their first AMI (ND-AMI), and 20 nondiabetic noncardiac controls. Eighty-three percent of D-AMI and 50% of ND-AMI had left ventricular ejection fractions below 2 SD of normal. Diabetics had a significantly lower resting LVEF than nondiabetics (p<0.05). All patients with LVEF < 35% were diabetics. LV mean ejection and filling rates were similar in diabetics and nondiabetics. While 72% of diabetics showed abnormal wall motion in 5 or more segments (out of 9), only 45% of the nondiabetics were this extensively affected. Seventy-two percent of the diabetics showed one or more of akinesis and 39% had one or more areas of dyskinesis, compared to 30% and 5% of the nondiabetics respectively. The authors conclude that the extent, as well as the severity of the left ventricular impairment is more evident in the diabetics than in the nondiabetics, following the first acute MI.
- Research Organization:
- V.A. Med. Ctr., Newington
- OSTI ID:
- 5960731
- Report Number(s):
- CONF-850611-; TRN: 87-039288
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 26:5; Conference: 32. annual meeting of the Society of Nuclear Medicine, Houston, TX, USA, 2 Jun 1985
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
HEART
DYNAMIC FUNCTION STUDIES
PATHOLOGICAL CHANGES
SCINTISCANNING
MYOCARDIAL INFARCTION
DIAGNOSIS
MYOCARDIUM
TECHNETIUM 99
DIAGNOSTIC USES
CARDIOVASCULAR DISEASES
CORRELATIONS
DIABETES MELLITUS
PATIENTS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
ENDOCRINE DISEASES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
METABOLIC DISEASES
MUSCLES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
TECHNETIUM ISOTOPES
USES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
551001 - Physiological Systems- Tracer Techniques
550901 - Pathology- Tracer Techniques