Combined technetium radioisotope penile plethysmography and xenon washout: A technique for evaluating corpora cavernosal inflow and outflow during early tumescence

Journal Article · Fri Mar 01 00:00:00 EST 1991 · Journal of Nuclear Medicine; (USA)

OSTI ID:5960282

Schwartz, A N; Graham, M M ^[1]

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1. Univ. of Washington Medical Center, Seattle (USA)

Combined technetium radioisotope penile plethysmography and xenon washout is a new technique that measures both corporal arterial inflow and venous sinusoidal outflow during early tumescence in patients with erectile dysfunction. Fourteen patients were studied using 99mTc-RBCs to measure inflow and 133Xe or 127Xe in saline to measure outflow. Tumescence was induced by injecting papaverine intracorporally. Peak corporal rates corrected for inflow (r = 0.88) and uncorrected for outflow (r = 0.91) and change in volume over 2 min centered around peak inflow (r = 0.96) all correlated with angiography. Outflow measurements did not correlate with intracorporal resistance. Thus, outflow rates alone could not be used to predict venous sinusoidal competence. Normal inflow rate is greater than 20 ml/min; probable normal 12-20; indeterminate inflow 7-12; and abnormal inflow less than 7 ml/min. Technetium-99m radioisotope penile plethysmography and xenon washout can be performed together and both provide a method for simultaneously evaluating the relationship between corporal inflow and outflow rates in patients with erectile dysfunction.

• OSTI ID: 5960282
• Journal Information: Journal of Nuclear Medicine; (USA), Vol. 32:3; ISSN 0161-5505
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
MALE GENITALS
BLOOD FLOW
UROGENITAL SYSTEM DISEASES
DIAGNOSIS
ERYTHROCYTES
ISOMERIC NUCLEI
PATIENTS
TECHNETIUM 99
XENON 127
XENON 133
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
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EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATERIALS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
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SECONDS LIVING RADIOISOTOPES
TECHNETIUM ISOTOPES
XENON ISOTOPES
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550601* - Medicine- Unsealed Radionuclides in Diagnostics