Single-dose radiation therapy for prevention of heterotopic ossification after total hip arthroplasty

Journal Article · Sat Dec 01 04:00:00 EST 1990 · Journal of Arthroplasty; (USA)

DOI:https://doi.org/10.1016/S0883-5403(08)80097-6· OSTI ID:5958414

Healy, W L; Lo, T C; Covall, D J; Pfeifer, B A; Wasilewski, S A ^[1]

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1. Lahey Clinic Medical Center, Burlington, MA (USA)

Single-dose radiation therapy was prospectively evaluated for its efficacy in prevention of heterotopic ossification in patients at high risk after total hip arthroplasty. Thirty-one patients (34 hips) were treated between 1981 and 1988. Risk factors for inclusion in the protocol included prior evidence of heterotopic ossification, ankylosing spondylitis, and diffuse idiopathic skeletal hyperostosis. Patients with hypertrophic osteoarthritis or traumatic arthritis with osteophytes were not included. Operations on 34 hips included 19 primary total and 11 revision total hip arthroplasties and 4 excisions of heterotopic ossification. All patients received radiotherapy to the hip after operation with a single dose of 700 centigray. Radiotherapy is recommended on the first postoperative day. After this single-dose radiation treatment, no patient had clinically significant heterotopic ossification. Recurrent disease developed in two hips (6%), as seen on radiography (grades 2 and 3). This series documents a 100% clinical success rate and a 94% radiographic success rate in preventing heterotopic ossification in patients at high risk after total hip arthroplasty. Single-dose radiotherapy is as effective as other radiation protocols in preventing heterotopic ossification after total hip arthroplasty. It is less expensive and easier to administer than multidose radiotherapy.

• OSTI ID: 5958414
• Journal Information: Journal of Arthroplasty; (USA), Journal Name: Journal of Arthroplasty; (USA) Vol. 5:4; ISSN JOARE; ISSN 0883-5403
• Country of Publication: United States
• Language: English

Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
BONE JOINTS
DISEASES
DOSES
MEDICAL SUPPLIES
MEDICINE
NUCLEAR MEDICINE
ORGANS
PATIENTS
PROSTHESES
RADIATION DOSES
RADIOLOGY
RADIOTHERAPY
RISK ASSESSMENT
SKELETAL DISEASES
SKELETON
THERAPY