Brominated 2- and 4-methyl-1,3-phenylene diisocyanates (2,4- and 2,6-toluylene diisocyanates)

Journal Article · Sun Mar 20 04:00:00 EST 1988 · J. Org. Chem. USSR (Engl. Transl.); (United States)

OSTI ID:5949456

Fetyukhin, V N; Kobrzhitskii, V V; Samarai, L I

The conditions were found for the selective introduction of a bromine atom into the ring and into the side chain of 2- and 4-methyl-1,3-phenylene diisocyanates. The effect of the bromine atom in the obtained bromine derivatives on the reactivity of the NCO groups in reactions with nucleophilic reagents was determined. The reaction of the isocyanate with bromine in the presence of a catalyst (iodine, ferric chloride) led to the product from monobromination in the ring. The use of iodine or ferric chloride as catalyst reduces the reaction time by half, but the yield does not increase.

• Research Organization: Institute of Organic Chemistry, Kiev (USSR)
• OSTI ID: 5949456
• Journal Information: J. Org. Chem. USSR (Engl. Transl.); (United States), Journal Name: J. Org. Chem. USSR (Engl. Transl.); (United States) Vol. 23:10; ISSN JOCYA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400201* -- Chemical & Physicochemical Properties
AMIDES
BROMINATION
CARBAMATES
CARBONIC ACID DERIVATIVES
CARBOXYLIC ACID SALTS
CATALYSIS
CATALYTIC EFFECTS
CHEMICAL REACTION KINETICS
CHEMICAL REACTION YIELD
CHEMICAL REACTIONS
CHLORIDES
CHLORINE COMPOUNDS
ELEMENTS
HALIDES
HALOGEN COMPOUNDS
HALOGENATION
HALOGENS
INFRARED SPECTRA
IODINE
IRON CHLORIDES
IRON COMPOUNDS
ISOCYANATES
KINETICS
MOLECULAR STRUCTURE
NMR SPECTRA
NONMETALS
ORGANIC BROMINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
REACTION KINETICS
SPECTRA
STRUCTURAL CHEMICAL ANALYSIS
TRANSITION ELEMENT COMPOUNDS
UREA
URETHANE
YIELDS