The role of Tc-99m IDA hepatobiliary and Tc-99m colloid hepatic imaging in primary biliary cirrhosis

Journal Article · Tue Jan 01 04:00:00 EST 1991 · Clinical Nuclear Medicine; (USA)

DOI:https://doi.org/10.1097/00003072-199101000-00002· OSTI ID:5944322

Aburano, T; Yokoyama, K; Shuke, N; Kinuya, S; Takayama, T; Tonami, N; Hisada, K ^[1]

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1. Kanazawa Univ. Hospital (Japan)

To assess the presence of primary biliary cirrhosis, 15 patients at various histopathologic stages were studied by Tc-99m IDA hepatobiliary and/or Tc-99m colloid hepatic imaging. In the earlier stages (I and II), seven of eight patients (88%) showed uniform hepatic retention of Tc-99m IDA. Of seven patients in the same stage, however, four (57%) showed no abnormality on Tc-99m colliod imaging. In three of these four negative patients (75%), uniform hepatic retention of Tc-99m IDA was noted. In the later stages (III and IV), all seven patients showed decreased clearance with or without delayed tracer appearance in the intestine and prominent hepatic retention on Tc-99m IDA imaging; with Tc-99m colloid imaging there was enlargement of the spleen and increased activity in the spleen and bone marrow. Thus, Tc-99m IDA imaging is considered to be more useful in revealing this functional disorder at the earlier stage of primary biliary cirrhosis and in evaluating progression from an earlier to a later stage of disease. Tc-99m colloid imaging also effectively evaluated progression.

• OSTI ID: 5944322
• Journal Information: Clinical Nuclear Medicine; (USA), Journal Name: Clinical Nuclear Medicine; (USA) Vol. 16:1; ISSN CNMED; ISSN 0363-9762
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BILIARY TRACT
BODY
BONE MARROW
COLLOIDS
COUNTING TECHNIQUES
DIAGNOSIS
DIGESTIVE SYSTEM
DIGESTIVE SYSTEM DISEASES
DISEASES
DISPERSIONS
HEMATOPOIETIC SYSTEM
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIVER CIRRHOSIS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SPLEEN
TECHNETIUM 99
TECHNETIUM ISOTOPES
TISSUES
YEARS LIVING RADIOISOTOPES