Fast atom bombardment mass spectrometry: a powerful technique for the study of polar molecules

Journal Article · Wed Sep 23 04:00:00 EDT 1981 · J. Am. Chem. Soc.; (United States)

DOI:https://doi.org/10.1021/ja00409a013· OSTI ID:5900762

Williams, D H; Bradley, C; Bojesen, G; Santikarn, S; Taylor, L C.E.

A study of a range of polar organic molecules by fast atom bombardment (FAB) mass spectrometry is reported. Compounds studied include organic salts, polar antibiotics, nucleoside phosphates, and underivatized peptides. In these classes of compounds, molecular weights in the range 300 to 2000 daltons have been routinely determined, operating in both positive and negative ion modes. Molecular weights of peptides are readily obtained on less than 1 nmol of material, and sequence information is conveniently deduced from sample sizes in the range 2 to 50 nmol.

• Research Organization: Cambridge Univ., England
• OSTI ID: 5900762
• Journal Information: J. Am. Chem. Soc.; (United States), Journal Name: J. Am. Chem. Soc.; (United States) Vol. 103:19; ISSN JACSA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400301* -- Organic Chemistry-- Chemical & Physicochemical Properties-- (-1987)
ANTI-INFECTIVE AGENTS
ANTIBIOTICS
DATA
DRUGS
EXPERIMENTAL DATA
INFORMATION
MASS SPECTROSCOPY
MOLECULAR WEIGHT
MOLECULES
NUCLEOSIDES
NUCLEOTIDES
NUMERICAL DATA
ORGANIC COMPOUNDS
PEPTIDES
POLAR COMPOUNDS
PROTEINS
RIBOSIDES
SALTS
SPECTROSCOPY