Furnace-generated acid aerosols: speciation and pulmonary effects

Journal Article · Wed Feb 01 04:00:00 EST 1989 · Environ. Health Perspect.; (United States)

DOI:https://doi.org/10.1289/ehp.8979147· OSTI ID:5900716

Amdur, M O; Chen, L C

Guinea pigs were exposed to ultrafine aerosols (less than 0.1 micron) of zinc oxide with a surface layer of sulfuric acid. These acid-coated aerosols are typical of primary emissions from smelters and coal combustors. Repeated daily 3-hr exposures for 5 days produce decrements in lung volumes and pulmonary diffusing capacity and elevations of lung weight/body weight ratio, protein, and number of neutrophils in pulmonary lavage fluid at concentrations of 20 micrograms/m3. A single 1-hr exposure to 20 micrograms/m3 causes increased bronchial reactivity. Higher concentrations of conventionally generated sulfuric acid mist are required to produce responses of similar magnitude.

• Research Organization: Massachusetts Institute of Technology, Cambridge (USA)
• OSTI ID: 5900716
• Journal Information: Environ. Health Perspect.; (United States), Journal Name: Environ. Health Perspect.; (United States) Vol. 79; ISSN EVHPA
• Country of Publication: United States
• Language: English

Related Subjects

01 COAL, LIGNITE, AND PEAT
016000 -- Coal
Lignite
& Peat-- Health & Safety
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACID RAIN
AEROSOLS
AIR POLLUTION
ANIMALS
ATMOSPHERIC PRECIPITATIONS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
CARBONACEOUS MATERIALS
CHALCOGENIDES
COAL
COLLOIDS
DISPERSIONS
DOSE-RESPONSE RELATIONSHIPS
ENERGY SOURCES
FOSSIL FUELS
FUELS
GUINEA PIGS
HAZARDS
HEALTH HAZARDS
HEATING
HYDROGEN COMPOUNDS
INHALATION
INORGANIC ACIDS
INTAKE
LAVAGE
LEUKOCYTES
LUNGS
MAMMALS
MATERIALS
NEUTROPHILS
ORGANS
OXIDES
OXYGEN COMPOUNDS
PARTICLE SIZE
POLLUTION
RAIN
RESPIRATORY SYSTEM
RODENTS
SENSITIVITY
SIZE
SOLS
SULFUR COMPOUNDS
SULFUR DIOXIDE
SULFUR OXIDES
SULFURIC ACID
TOXICITY
VERTEBRATES