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Rapid aquatic toxicity assay utilizing labeled thymidine incorporation in sea urchin embryos

Technical Report ·
OSTI ID:5896126
;
Aquatic toxicity was evaluated in the sea urchin embryo (Arbacea punctulata) by the inhibition of tritiated thymidine incorporation after a brief exposure to toxic chemicals. Arbacia is a useful surrogate species for assay: well-studied, easily cultured and fertile virtually year round. The simplicity and speed of this test system lends itself to screening large numbers of compounds, mixtures or water samples.
Research Organization:
Environmental Protection Agency, Narragansett, RI (USA). Environmental Research Lab.
OSTI ID:
5896126
Report Number(s):
PB-86-111564/XAB; ERLN-605
Country of Publication:
United States
Language:
English

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Related Subjects

520200 -- Environment
Aquatic-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
550500* -- Metabolism
59 BASIC BIOLOGICAL SCIENCES
ANIMALS
AQUATIC ORGANISMS
BIOASSAY
CHEMICAL ANALYSIS
ECHINODERMS
EMBRYOS
INVERTEBRATES
ISOTOPE APPLICATIONS
MATERIALS
METABOLISM
SAMPLING
SCREENING
SEA URCHINS
TOXIC MATERIALS
TOXICITY
TRACER TECHNIQUES