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Synthesis of endo,endo-2,5-bis((diphenylphosphino)methyl)bicyclo(2. 2. 1)heptane, a chelating diphosphine with a natural bite angle of 120 degree

Journal Article · · Journal of Organic Chemistry; (United States)
DOI:https://doi.org/10.1021/jo00291a061· OSTI ID:5891662
;  [1]
  1. Univ. of Wisconsin, Madison (United States)
One of the key intermediates in rhodium-catalyzed hydroformylation reactions is a trigonal-bipyramidal rhodium diphosphine species. The two phosphines in (R{sub 3}P){sub 2}(CO){sub 2}RhH have the possibility of occupying two axial, two equatorial, or one axial and one equatorial position. Use of chelating ligands such as DIPHOS, which has a preferred bite angle (P-M-P) of about 90{degree} allows study of locked axial, equatorial diphosphine catalysts. Because of the authors' interest in hydroformylation, they have initiated a program to design and synthesize chelating diphosphines which have a constrained bite angle near 120{degree} for selective diequatorial coordination. Here they describe the synthesis and characterization of the racemic diphosphine.
OSTI ID:
5891662
Journal Information:
Journal of Organic Chemistry; (United States), Journal Name: Journal of Organic Chemistry; (United States) Journal Issue: 4 Vol. 55:4; ISSN JOCEA; ISSN 0022-3263
Country of Publication:
United States
Language:
English