Determination of chloroacetylchloride in air by high-performance liquid chromatography
Journal Article
·
· Anal. Chem.; (United States)
An HPLC procedure has been developed for the determination of chloroacetyl chloride (CAC) in air. CAC is collected on Tenax-GC coated with 9-((N-methylamino)methyl)anthracene (MAMA) packed in glass tubes. The MAMA acts as an in situ derivatizing agent for CAC, and the resulting amide is solvent desorbed from the Tenax support and analyzed by HPLC with fluorescence detection. Standard vapor concentrations of CAC were generated in silanized glass for laboratory validation in the range of 5-2500 ppb CAC based on a 5-L air sample. The average recovery was 79% with a pooled relative standard deviation of 0.083. Up to 100 L of air was sampled and similar recoveries were obtained implying a practical limit of quantification 1 ppb. The limit of detection for the MAMA derivative of CAC, N-(9-anthracenylmethyl)-2-chloro-N-methylacetamide, under optimal conditions is less than 1 pg. 12 references, 1 figure, 2 tables.
- Research Organization:
- Monsanto Agricultural Co., St. Louis, MO
- OSTI ID:
- 5891623
- Journal Information:
- Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 58:4; ISSN ANCHA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102* -- Chemical & Spectral Procedures
500200 -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
ACETALS
ADSORPTION
AIR
AIR POLLUTION MONITORING
AIR SAMPLERS
ANTHRACENE
AROMATICS
CHEMICAL ANALYSIS
CHEMICAL REACTIONS
CHLORIDES
CHLORINE COMPOUNDS
CHROMATOGRAPHY
CONDENSED AROMATICS
DATA
DERIVATIZATION
DESORPTION
EQUIPMENT
ETHERS
EXPERIMENTAL DATA
FLUIDS
GASES
HALIDES
HALOGEN COMPOUNDS
HYDROCARBONS
INDUSTRIAL PLANTS
INFORMATION
LIQUID COLUMN CHROMATOGRAPHY
NUMERICAL DATA
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
PERFORMANCE
QUANTITATIVE CHEMICAL ANALYSIS
SAMPLERS
SEPARATION PROCESSES
SORPTION
SORPTIVE PROPERTIES
SURFACE PROPERTIES
TRACE AMOUNTS
400102* -- Chemical & Spectral Procedures
500200 -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
ACETALS
ADSORPTION
AIR
AIR POLLUTION MONITORING
AIR SAMPLERS
ANTHRACENE
AROMATICS
CHEMICAL ANALYSIS
CHEMICAL REACTIONS
CHLORIDES
CHLORINE COMPOUNDS
CHROMATOGRAPHY
CONDENSED AROMATICS
DATA
DERIVATIZATION
DESORPTION
EQUIPMENT
ETHERS
EXPERIMENTAL DATA
FLUIDS
GASES
HALIDES
HALOGEN COMPOUNDS
HYDROCARBONS
INDUSTRIAL PLANTS
INFORMATION
LIQUID COLUMN CHROMATOGRAPHY
NUMERICAL DATA
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
PERFORMANCE
QUANTITATIVE CHEMICAL ANALYSIS
SAMPLERS
SEPARATION PROCESSES
SORPTION
SORPTIVE PROPERTIES
SURFACE PROPERTIES
TRACE AMOUNTS