Immunoreactive luteinizing hormone-releasing hormone in the seminal plasma and human semen parameters
Journal Article
·
· Fert. Steril.; (United States)
OSTI ID:5880664
A luteinizing hormone-releasing hormone (LH-RH)-like substance has been detected in human seminal plasma by a radioimmunoassay (RIA) with a highly specific anti-LH-RH antiserum. The seminal samples - not only the plasma itself but also the sample extracted by an acid/alcohol method - showed satisfactory displacement curves in our RIA system. The relationship between fertility and the LH-RH values in the seminal plasma was studied by comparing the peptide levels with sperm concentration and motility. By these two parameters, 103 samples were divided into four groups. In the low-concentration groups (oligozoospermic patients), the hormonal concentrations differed significantly between those specimens demonstrating good and poor motility. These data suggest that this immunoreactive LH-RH may play a role in human spermatogenesis.
- Research Organization:
- Keio Univ., Tokyo, Japan
- OSTI ID:
- 5880664
- Journal Information:
- Fert. Steril.; (United States), Journal Name: Fert. Steril.; (United States) Vol. 43:4; ISSN FESTA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
551001 -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
DIAGNOSIS
FERTILITY
GAMETOGENESIS
HORMONES
IMMUNOASSAY
IMMUNOLOGY
ISOTOPE APPLICATIONS
LH-RH
LIBERINS
MALE GENITALS
MATERIALS
ORGANS
PATIENTS
PEPTIDE HORMONES
PITUITARY HORMONES
RADIOASSAY
RADIOIMMUNOASSAY
RADIOIMMUNOLOGY
REPRODUCTIVE DISORDERS
SPERMATOGENESIS
TRACER TECHNIQUES
551001 -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
DIAGNOSIS
FERTILITY
GAMETOGENESIS
HORMONES
IMMUNOASSAY
IMMUNOLOGY
ISOTOPE APPLICATIONS
LH-RH
LIBERINS
MALE GENITALS
MATERIALS
ORGANS
PATIENTS
PEPTIDE HORMONES
PITUITARY HORMONES
RADIOASSAY
RADIOIMMUNOASSAY
RADIOIMMUNOLOGY
REPRODUCTIVE DISORDERS
SPERMATOGENESIS
TRACER TECHNIQUES