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Treatment of choice for localized poorly differentiated adenocarcinoma of the prostate

Journal Article · · Am. J. Clin. Oncol.; (United States)
; ;

Of 286 evaluable patients definitively irradiated for adenocarcinoma of the prostate, 71 with Stage B2 and C poorly differentiated lesions were studied. Forty-six patients were treated with external beam therapy and 25 with 125I implantation and pelvic lymph node dissection. Within both the external beam and the 125I treatment groups, the local recurrence rate was noticeably higher in the Stage C than in the Stage B2 tumors. Moreover, the incidence of local failure was significantly increased in those patients treated with 125I implantation, 56% vs. 24% (p = 0.008), suggesting that external beam irradiation may be the treatment of choice for localized, poorly differentiated prostatic tumors.

Research Organization:
Eastern Virginia Medical School, Norfolk
OSTI ID:
5880374
Journal Information:
Am. J. Clin. Oncol.; (United States), Journal Name: Am. J. Clin. Oncol.; (United States) Vol. 6; ISSN AJCOD
Country of Publication:
United States
Language:
English

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Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
550604 -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BODY
CARCINOMAS
DAYS LIVING RADIOISOTOPES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
EVALUATION
GLANDS
IMPLANTS
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOTOPES
MALE GENITALS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
PROSTATE
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
THERAPY