Electrochemically-modulated liquid chromatography (EMLC): Column design, retention processes, and applications

Thesis/Dissertation · Wed Oct 08 04:00:00 EDT 1997

DOI:https://doi.org/10.2172/587884· OSTI ID:587884

Ting, En -Yi ^[1]

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1. Iowa State Univ., Ames, IA (United States)

This work describes the continued development of a new separation technique, electrochemically-modulated liquid chromatography (EMLC), from column design, retention mechanisms to pharmaceutical applications. The introduction section provides a literature review of the technique as well as a brief overview of the research in each of the chapters. This section is followed by four chapters which investigate the issues of EMLC column design, the retention mechanism of monosubstituted aromatic compounds, and the EMLC-based applications to two important classes of pharmaceutical compounds (i.e., corticosteroids and benzodiazepines). These four sections have been removed to process separately for inclusion on the database. The dissertation concludes with a general summary, a prospectus, and a list of references cited in the General Introduction. 32 refs.

• Research Organization: Ames Lab., IA (United States)
• Sponsoring Organization: USDOE Office of Energy Research (ER); National Science Foundation (NSF)
• DOE Contract Number: W-7405-ENG-82
• OSTI ID: 587884
• Report Number(s): IS-T--1817; ON: DE98004641
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
ADSORBENTS
AROMATICS
CORTICOSTEROIDS
DESIGN
DRUGS
LIQUID COLUMN CHROMATOGRAPHY
ORGANIC NITROGEN COMPOUNDS