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Description and performance comparison of commercial and prototype dual photon absorptiometry (DPA) systems

Conference · · J. Nucl. Med.; (United States)
OSTI ID:5875542
DPA has become of major interest for clinical measurements of bone mineral (BM) in the axial skeleton. Several commercial instruments are now available. The objective of this paper is a description and comparison of these instruments with some of the instruments used in clinical research laboratories. /sup 153/Gd is almost exclusively used as a source (1-1.5Ci). All instruments use NaI(T1) detectors. Detector collimator sizes vary from about 0.6 to 1.3 cm diameter. Linearity, accuracy and reproducibility of BM measurements were evaluated by scanning a series of ashed bones in 20 cm of water. Reproducibility was studied by performing multiple scans of ashed bones and a cadaver spine, CV being less than 2.1% for the spine. Minimum performance criteria for a clinical bone mineral test is a reproducibility of less than 3%. Dosimetry studies conducted to date show a peak skin dose of 18 mrad (0.18mGy). Additional dosimetry measurements are presently being performed. The authors conclude that the commercial DPA units provide results which are clinically acceptable and comparable to the prototype systems.
Research Organization:
Mayo Clinic/Foundation, Rochester, MN
OSTI ID:
5875542
Report Number(s):
CONF-850611-
Conference Information:
Journal Name: J. Nucl. Med.; (United States) Journal Volume: 26:5
Country of Publication:
United States
Language:
English

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