Effect of ionizing radiation on shock-elicited aggression of male rats. Final report 1 Jan 80-1 Jan 81

Technical Report · Mon Jun 01 00:00:00 EDT 1981

OSTI ID:5870704

Burke, Jr, R D; Mattsson, J L; Fischer, J R

Several pairs of male Sprague-Dawley rats were exposed to either 0, 350, 700, 1400, or 2100 rads of Co60 radiation at 250 rads/min. Pairs were then tested for aggression at 20 min, 6 h, 72 h, and 7 d post irradiation. Each test session lasted for 5 min and consisted of 50 3-W shocks 0.5-s duration with a 5.5-s shock-shock interval. Scores indicated how many aggressive interactions took place during the 50 intershock intervals. Aggressive interactions in the 700-rad group increased (p <,025) at 72 h post irradiation. Secondarily, to validate the experimental procedure, a known aggression-reducing drug was tested on a different set of rats. Chlorpromazine hydrochloride, 2 mg/kg, intramuscular, caused a decrease in aggression 120 min post injection (p <.01).

• Research Organization: School of Aerospace Medicine, Brooks AFB, TX (USA)
• OSTI ID: 5870704
• Report Number(s): AD-A-103329/9
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BEHAVIOR
BIOLOGICAL RADIATION EFFECTS
GAMMA RADIATION
MALES
NERVES
NEUROLOGY
RATS
ANIMALS
BIOLOGICAL EFFECTS
ELECTROMAGNETIC RADIATION
IONIZING RADIATIONS
MAMMALS
MEDICINE
NERVOUS SYSTEM
RADIATION EFFECTS
RADIATIONS
RODENTS
VERTEBRATES
560152* - Radiation Effects on Animals- Animals