Hyperfunctioning metastatic follicular thyroid carcinoma in Pendred's syndrome

Journal Article · Mon Apr 15 00:00:00 EDT 1991 · Cancer (Philadelphia); (USA)

DOI:https://doi.org/10.1002/1097-0142(19910415)67:8<2191::AID-CNCR2820670831>3.0.CO;2-B· OSTI ID:5853236

Abs, R; Verhelst, J; Schoofs, E; De Somer, E ^[1]

---

1. University Hospital, Antwerp (Belgium)

A 66-year-old woman with Pendred's syndrome underwent a partial thyroidectomy when she was 17 years old. At the age of 52 years, she had a second thyroid operation because of hyperthyroidism due to a toxic multinodular goiter with a mediastinal extension consisting of several separate nodules. Five years later a hyperfunctioning metastatic follicular carcinoma was diagnosed histologically. After treatment with radioactive iodine, the patient was well. To the authors' knowledge, this is the first description of a metastatic follicular thyroid carcinoma in Pendred's syndrome and the first report of hyperthyroidism occurring after malignant degeneration of a dyshormonogenetic goiter.

• OSTI ID: 5853236
• Journal Information: Cancer (Philadelphia); (USA), Journal Name: Cancer (Philadelphia); (USA) Vol. 67:8; ISSN 0008-543X; ISSN CANCA
• Country of Publication: United States
• Language: English

Related Subjects

550604* -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMALS
BODY
CARCINOMAS
DISEASES
ENDOCRINE DISEASES
ENDOCRINE GLANDS
GLANDS
HYPERTHYROIDISM
IODINE ISOTOPES
ISOTOPES
MAMMALS
MAN
MEDICINE
METASTASES
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
PRIMATES
RADIOLOGY
RADIOTHERAPY
SURGERY
THERAPY
THYROID
THYROIDECTOMY
VERTEBRATES