Preparation and configurational analysis of the stereoisomers of /beta/,/gamma/-bidentate Rh(H/sub 2/O)/sub 4/ATP and /alpha/,/beta/,/gamma/-tridentate Rh(H/sub 2/O)/sub 3/ATP. A new class of enzyme active site probes

Journal Article · Wed Nov 16 00:00:00 EST 1988 · Inorg. Chem.; (United States)

DOI:https://doi.org/10.1021/ic00296a012· OSTI ID:5852735

Lu, Z; Shorter, A L; Lin, I; Dunaway-Mariano, D

Exchange-inert Co(III) and Cr(III) complexes of polyphosphates have proved to be useful probes of the structural and biochemical properties of naturally occurring Mg/sup II/(polyphosphate) complexes. However, applications of these complexes are not without limitations. The Cr/sup III/(polyphosphate) probes or their enzymatic products cannot be used in NMR methods because of the paramagnetic nature of the Cr(III) metal. The redox properties of the metal in the Co/sup III/(polyphosphate) complexes require that they also be coordinated to a nitrogen-containing ligand. This requirement is not always convenient. This work reported herein was undertaken to create a new class of exchange-inert metal polyphosphate complexes that contain a metal that is both diamagnetic and redox stable. The preparation, properties, and configurational analysis of the stereoisomers of /beta/, /gamma/-bidentate Rh(H/sub 2/O)/sub 4/ATP (ATP = adenosine 5'-triphosphate) and /alpha/,/beta/,/gamma/-tridentate Rh(H/sub 2/O)/sub 3/ATP are described. 12 refs., 5 figs.

• Research Organization: Univ. of Maryland, College Park (USA)
• OSTI ID: 5852735
• Journal Information: Inorg. Chem.; (United States), Vol. 27:23
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
ADENOSINE
CHEMICAL PREPARATION
PHOSPHATES
RHODIUM COMPLEXES
EXPERIMENTAL DATA
NMR SPECTRA
OXYGEN 18
PHOSPHORUS 31
COMPLEXES
DATA
EVEN-EVEN NUCLEI
INFORMATION
ISOTOPES
LIGHT NUCLEI
NUCLEI
NUCLEOSIDES
NUCLEOTIDES
NUMERICAL DATA
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
OXYGEN COMPOUNDS
OXYGEN ISOTOPES
PHOSPHORUS COMPOUNDS
PHOSPHORUS ISOTOPES
RIBOSIDES
SPECTRA
STABLE ISOTOPES
SYNTHESIS
TRANSITION ELEMENT COMPLEXES
400201* - Chemical & Physicochemical Properties
400202 - Isotope Effects
Isotope Exchange
& Isotope Separation