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Multinuclear ( sup 195 Pt, sup 15 N, sup 13 C) NMR studies of the reactions between cis-diaminediaquaplatinum(II) complexes and aminomalonate

Journal Article · · Inorganic Chemistry; (USA)
DOI:https://doi.org/10.1021/ic00350a021· OSTI ID:5851964
The reactions between cis-PtAm{sub 2}(H{sub 2}O){sub 2}{sup 2+} (Am = RNH{sub 2}, aziridine; Am{sub 2} = ethylenediamine, 1,2-diaminocyclohexane) and aminomalonate (amal) show that initially the O,O chelate with the 1,1-dicarboxylic group is formed and that subsequently the kinetic product isomerizes to yield the thermodynamically stable N,O chelate. The identity of the thermodynamic product was established by {sup 195}Pt, {sup 15}N, and {sup 13}C NMR spectroscopy. The formation of the unidentate intermediate adduct (PtAm{sub 2}(H{sub 2}O)(amal-O)){sup +} could not be observed by {sup 15}N NMR spectroscopy due to the fast transformation to give the (PtAm{sub 2}(amal-O,O)){sup +} chelate. {sup 195}Pt NMR studies also show that 22-h reactions in DMF between cis-PtAm{sub 2}LL (L = DMF, NO{sub 3}{sup {minus}}) and amidomalonates resulted in isomeric mixtures in which the O,O:N,O ratio ranged between 3:2 and 5:1. 33 refs., 5 figs., 2 tabs.
OSTI ID:
5851964
Journal Information:
Inorganic Chemistry; (USA), Journal Name: Inorganic Chemistry; (USA) Vol. 29:25; ISSN 0020-1669; ISSN INOCA
Country of Publication:
United States
Language:
English