Photobiological fundamentals of low-power laser therapy

Journal Article · Thu Oct 01 04:00:00 EDT 1987 · IEEE J. Quant. Electron.; (United States)

DOI:https://doi.org/10.1109/JQE.1987.1073236· OSTI ID:5851498

Karu, T I

Quantitative studies of the action of low-power visible nonchromatic light on various cells (E. coli, yeasts, HeLa) were performed to find irradiation conditions (wavelength, dose, intensity) conducive to vital activity stimulation. The action spectra of visible light on DNA and RNA synthesis in HeLa cells have maxima near 404, 620, 680, 760, and 830 nm. Growth simulation of E. coli is at a maximum when irradiated at 404, 454, 570, 620, and 750 nm, and biomass accumulation stimulation in yeasts has a maxima at 404, 570, 620, 680, and 760 nm. Absorption of quanta is only a trigger for the rearrangement of cellular metabolism, with photosignal transduction being effected by standard cellular means such as changes in the cAMP level. Respiratory chain components are discussed as primary photoacceptors. It is concluded that ''laser biostimulation'' is of a photobiological nature, and low-power laser effects can be related to well-known photobiological phenomena.

• Research Organization: Laser Technology Research Center, Academy of Sciences of the U.S.S.R., 142092 Moscow Region, Troitzk
• OSTI ID: 5851498
• Journal Information: IEEE J. Quant. Electron.; (United States), Journal Name: IEEE J. Quant. Electron.; (United States) Vol. QE-23:10; ISSN IEJQA
• Country of Publication: United States
• Language: English

Related Subjects

550600* -- Medicine
62 RADIOLOGY AND NUCLEAR MEDICINE
BACTERIA
BIOLOGICAL EFFECTS
ELECTROMAGNETIC RADIATION
LASER RADIATION
MICROORGANISMS
OPTICAL PROPERTIES
PHYSICAL PROPERTIES
RADIATIONS
THERAPEUTIC USES
THERAPY
USES