Effects of environmentally differential rearing upon maze performance in prenatally irradiated microcephalic rats

Journal Article · Wed Dec 01 00:00:00 EST 1982 · Teratology; (United States)

DOI:https://doi.org/10.1002/tera.1420260302· OSTI ID:5849160

Seo, M L; Inouye, M; Kiyono, S; Shibagaki, M

Pregnant rats received 100 rads of X-irradiation on day 17 of gestation. Control pregnant rats were sham-irradiated on the same gestation day. The male offspring were reared under environmentally enriched, standard colony, and impoverished conditions for 30 days after weaning. Then the Hebb-Williams maze test was carried out. All the prenatally X-irradiated rats were microcephalic: their mean cerebral wet weight was 15.5% less than controls. The effect of X-irradiation was not significant in error scores and running times, whereas the effect of environment was significant in these items; initial and total error scores and running times were decreased in enriched groups compared to impoverished groups in controls as well as in X-irradiated animals.

• Research Organization: Department of Physiology, Institute for Developmental Research, Aichi Prefectural Colony, Japan
• OSTI ID: 5849160
• Journal Information: Teratology; (United States), Vol. 26:3
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
RATS
BIOLOGICAL RADIATION EFFECTS
BEHAVIOR
DIET
PERFORMANCE
PRENATAL IRRADIATION
X RADIATION
ANIMALS
BIOLOGICAL EFFECTS
ELECTROMAGNETIC RADIATION
IONIZING RADIATIONS
IRRADIATION
MAMMALS
PRENATAL EXPOSURE
RADIATION EFFECTS
RADIATIONS
RODENTS
VERTEBRATES
560152* - Radiation Effects on Animals- Animals