Sympathetic ophthalmia complicating helium ion irradiation of a choroidal melanoma

Journal Article · Sun Nov 01 04:00:00 EST 1987 · Arch. Ophthalmol. (Chicago); (United States)

DOI:https://doi.org/10.1001/archopht.1987.01060110107042· OSTI ID:5844298

Fries, P D; Char, D H; Crawford, J B; Waterhouse, W

Sympathetic ophthalmia was diagnosed 49 months after helium ion irradiation of a left choroidal melanoma. The patient maintained good vision until 18 months after therapy, when she developed neovascular glaucoma. This complication required multiple therapeutic procedures, including topical anti-inflammatory and antiglaucomatous drops, 360 degrees peripheral panretinal cryoblation, and a single 180 degrees application of inferior cyclocryotherapy over a 2 1/2-year period. Four weeks after the cyclocryotherapy, inflammation was noted in both eyes, and, one month later, enucleation of the left sympathogenic eye was performed. Serial histopathologic sections showed a full-thickness, fibrovascular, scleral scar and tantalum marker ring suture without uveal incarceration. Penetrating surgical trauma, a uveal melanoma, and multiple nonpenetrating treatments resulted in the development of sympathetic ophthalmia.

• Research Organization: Univ. of California, San Francisco
• OSTI ID: 5844298
• Journal Information: Arch. Ophthalmol. (Chicago); (United States), Journal Name: Arch. Ophthalmol. (Chicago); (United States) Vol. 105:11; ISSN AROPA
• Country of Publication: United States
• Language: English

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