Comparison of tissue ablation with pulsed holmium and thulium lasers
- Massachusetts General Hospital, Boston, MA (US)
The ablation rates and tissue effects produced by a pulsed holmium laser (wavelength 2.12 {mu}m, pulse duration 250 {mu}s) and a pulsed thulium laser (wavelength 2.01 {mu}m, pulse duration 250 {mu}s) are compared. Because the absorption coefficient of water is almost three times greater at the shorter wavelength (65 versus 24 cm{sup {minus}1}), the thulium laser should have a significantly lower threshold of ablation and produce significantly less residual thermal injury. These hypotheses were tested in vitro. Ablation rates were measured using fresh liver and a mass loss technique and found to increase linearly with delivered radiant exposure. The threshold radiant exposure for ablation was derived from the mass loss measurements and found to be 36 J/cm{sup 2} for the holmium laser and 29 J/cm{sup 2} for the thulium laser. The corresponding heats of ablation were 10 kJ/cm{sup 3} for the holmium laser and 9.7 kJ/cm{sup 3} for the thulium laser. These values were not statistically different.
- OSTI ID:
- 5840564
- Journal Information:
- IEEE Journal of Quantum Electronics (Institute of Electrical and Electronics Engineers); (USA), Vol. 26:12; ISSN 0018-9197
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
SOLID STATE LASERS
COMPARATIVE EVALUATIONS
TISSUES
ABLATION
CORRELATIONS
ENERGY ABSORPTION
HOLMIUM
LIVER CELLS
NEAR INFRARED RADIATION
PULSES
THRESHOLD ENERGY
THULIUM
WATER
ABSORPTION
ANIMAL CELLS
BODY
ELECTROMAGNETIC RADIATION
ELEMENTS
ENERGY
HYDROGEN COMPOUNDS
INFRARED RADIATION
LASERS
METALS
OXYGEN COMPOUNDS
RADIATIONS
RARE EARTHS
SOMATIC CELLS
560120* - Radiation Effects on Biochemicals
Cells
& Tissue Culture