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SPECT quantification of technetium-99m microspheres within the canine lung

Journal Article · · J. Comput. Assist. Tomogr.; (United States)
Attenuation compensated single photon emission CT (SPECT) count rates of /sup 99m/Tc microsphere activities from 151 selected small regions of interest (ROIs) in an intact canine thorax were compared with the count rates obtained from scintillation camera images of similar ROIs from frozen slices of the thorax. A first-order method was used to compensate the SPECT and scintillation camera images for the effect of Compton scattering. The SPECT and scintillation camera count rates correlated well: r . 0.95 (RMS error 4.8 counts/s) for 19 X 19 X 13 mm thick ROIs. The authors conclude that regional quantification of /sup 99m/Tc microspheres within the dog thorax is possible using camera-based SPECT systems.
Research Organization:
Duke Univ. Medical Center, Durham, NC
OSTI ID:
5835927
Journal Information:
J. Comput. Assist. Tomogr.; (United States), Journal Name: J. Comput. Assist. Tomogr.; (United States) Vol. 9:1; ISSN JCATD
Country of Publication:
United States
Language:
English