An interdisciplinary approach to investigate the etiology of lung cancer in Xuan Wei, China: A study on mutagenicity, carcinogenicity, and human lung cancer risk from indoor exposure to combustion emissions

Conference · · Archives of Environmental Health; (United States)

OSTI ID:5817771

Mumford, J; Chapman, R; Harris, D; He, X; Lee, X; Cao, S

This paper reports studies of chemical, physical, and toxicological characteristics of indoor air from Xuan Wei homes and links results to human lung chance. Indoor air particles (PM{sub 10}) were collected during cooking from Xuan Wei homes in two communes with high and low lung cancer mortality rates and where smoky coal, smokeless coal, and wood were used. The results showed that Xuan Wei residents who used smoky coal were exposed to extremely high concentrations (> 20 mg/m{sup 3}) of mostly submicron particles. These particles consisted mostly of organic matter (72%), which showed mutagenicity and carcinogenicity, especially in aromatic and polar fractions. These residents were exposed to carcinogenic polycyclic aromatic hydrocarbons at comparable or higher levels than occupational settings. The smoky coal emissions showed much higher mutagenicity and carcinogenicity than did the wood or smokeless coal emissions.

• OSTI ID: 5817771
• Report Number(s): CONF-9008208-; CODEN: AEHLA
• Journal Information: Archives of Environmental Health; (United States), Vol. 46:3; Conference: 2. annual meeting of the International Society for Environmental Epidemiology (ISEE), Berkeley, CA (United States), 13-15 Aug 1990; ISSN 0003-9896
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
01 COAL, LIGNITE, AND PEAT
54 ENVIRONMENTAL SCIENCES
COMBUSTION PRODUCTS
CARCINOGENESIS
LUNGS
NEOPLASMS
ETIOLOGY
CHINA
COAL
EPIDEMIOLOGY
INDOOR AIR POLLUTION
MORTALITY
MUTAGENESIS
PARTICULATES
POLLUTANTS
POLYCYCLIC AROMATIC HYDROCARBONS
AIR POLLUTION
AROMATICS
ASIA
BODY
CARBONACEOUS MATERIALS
DISEASES
ENERGY SOURCES
FOSSIL FUELS
FUELS
HYDROCARBONS
MATERIALS
ORGANIC COMPOUNDS
ORGANS
PARTICLES
PATHOGENESIS
POLLUTION
RESPIRATORY SYSTEM
560300* - Chemicals Metabolism & Toxicology
016000 - Coal
Lignite
& Peat- Health & Safety
540120 - Environment
Atmospheric- Chemicals Monitoring & Transport- (1990-)