Metabolism of chlorobenzene and hexachlorobenzene by the zebra fish, Brachydanio rerio

Journal Article · Wed Feb 01 04:00:00 EST 1989 · Bull. Environ. Contam. Toxicol.; (United States)

DOI:https://doi.org/10.1007/BF01699408· OSTI ID:5815016

Kasokat, T; Nagel, R; Urich, K

It is now becoming evident that in many cases metabolites have a greater toxic potential than the parent xenobiotic exposed. For this reason, the knowledge of biotransformation pathways of xenobiotics plays a substantial role in environmental monitoring programs. The zebra fish (Brachydanio rerio, Hamilton-Buchanan) has received increased attention as a model species for freshwater fish in environmental surveillance programs to evaluate potential health and impacts of anthropogenic chemicals. The metabolism of phenol and various substituted phenols in zebra fish has recently been studied. The purpose of the present study was to examine the metabolism of chlorobenzene and hexachlorobenzene (HCB), by the zebra fish following in vivo exposure of sublethal concentrations in the water.

• Research Organization: University Mainz (West Germany)
• OSTI ID: 5815016
• Journal Information: Bull. Environ. Contam. Toxicol.; (United States), Journal Name: Bull. Environ. Contam. Toxicol.; (United States) Vol. 42:2; ISSN BECTA
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AROMATICS
BENZENE
CARBON 14 COMPOUNDS
CHLORINATED AROMATIC HYDROCARBONS
CHROMATOGRAPHY
HALOGENATED AROMATIC HYDROCARBONS
HYDROCARBONS
IN VIVO
LABELLED COMPOUNDS
LIQUID COLUMN CHROMATOGRAPHY
METABOLISM
METABOLITES
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
POLLUTION
SEPARATION PROCESSES
WATER POLLUTION