Cutaneous effects of exposure to polybrominated biphenyls (PBBs): the Michigan PBB incident
Journal Article
·
· Environ. Res.; (United States)
- Univ. of Michigan, Ann Arbor
In 1973 an environmental accident occurred in northern Michigan in which 1000-2000 pounds of the toxic fire retardant polybrominated biphenyl (PBB) was added to the livestock food supply of much of northern Michigan. PBB is highly lipophilic, poorly metabolized, and biocumulative. It subsequently entered the human food chain of the entire state of Michigan. Health effects were noted in contaminated animals and among exposed farmers some months after the contamination; these often included cutaneous problems. Three years later a multidisciplinary study of the farming population was undertaken. Detected cutaneous abnormalities included halogen acne, hair loss, skin redness, skin peeling, and scaling, itching, increased sweating, and increased growth of fingernails and toenails. The mechanisms underlying these effects are unknown. PBBs appear to be etiologically implicated for significant cutaneous toxicity.
- OSTI ID:
- 5814720
- Journal Information:
- Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 29:1; ISSN ENVRA
- Country of Publication:
- United States
- Language:
- English
Similar Records
PBB episode in Michigan: an overall appraisal
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Journal Article
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Mon Dec 31 23:00:00 EST 1984
· CRC Crit. Rev. Toxicol.; (United States)
·
OSTI ID:5858015
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Journal Article
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Wed Dec 31 23:00:00 EST 1986
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·
OSTI ID:5393570
Determinants of polychlorinated biphenyls (PCBs), polybrominated biphenyls (PBBs), and dichlorodiphenyl trichloroethane (DDT) levels in the sera of young children
Journal Article
·
Sun Oct 01 00:00:00 EDT 1989
· American Journal of Public Health; (USA)
·
OSTI ID:5477547
Related Subjects
552000 -- Public Health
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
99 GENERAL AND MISCELLANEOUS
ACCIDENTS
ANIMAL FEEDS
AROMATICS
BODY
BROMINATED AROMATIC HYDROCARBONS
CONTAMINATION
EPILATION
ERYTHEMA
FEDERAL REGION V
FOOD
FOOD CHAINS
HAIR
HALOGENATED AROMATIC HYDROCARBONS
HAZARDS
HEALTH HAZARDS
HUMAN POPULATIONS
MICHIGAN
NORTH AMERICA
ORGANIC BROMINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
POPULATIONS
PUBLIC HEALTH
SKIN
SYMPTOMS
TOXICITY
USA
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
99 GENERAL AND MISCELLANEOUS
ACCIDENTS
ANIMAL FEEDS
AROMATICS
BODY
BROMINATED AROMATIC HYDROCARBONS
CONTAMINATION
EPILATION
ERYTHEMA
FEDERAL REGION V
FOOD
FOOD CHAINS
HAIR
HALOGENATED AROMATIC HYDROCARBONS
HAZARDS
HEALTH HAZARDS
HUMAN POPULATIONS
MICHIGAN
NORTH AMERICA
ORGANIC BROMINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
POPULATIONS
PUBLIC HEALTH
SKIN
SYMPTOMS
TOXICITY
USA