Pulmonary uptake of Tc-99m-labeled methylene diphosphonate in a patient with aparathyroid adenoma

Journal Article · Thu Oct 01 04:00:00 EDT 1981 · J. Nucl. Med.; (United States)

OSTI ID:5808607

Herry, J Y; Chevet, D; Moisan, A

Intense diffuse uptake of Tc-99m-labeled methylene diphosphonate was seen in both lungs of a patient submitted to surgery for a primary parathyroid adenoma. Five scans performed over the 3 yr following the operation showing persistence of lung uptake despite restoration of normal blood calcium concentration. Mild chronic renal failure caused by the hypercalcemia also persisted postoperatively. The present case confirms that pulmonary uptake of a bone tracer can occur asymptomatically when both hypercalcemia and renal failure are present. Lung uptake of a bone tracer probably reflects tissue deposition of hydroxapatite rather than of amorphous structures. Correction of the hypercalcemia failed to resolve the abnormal scan pictures.

• Research Organization: Hopital de Pontchaillou, Rennes, France
• OSTI ID: 5808607
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 22:10; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ADENOMAS
ALKALINE EARTH METALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BIOMEDICAL RADIOGRAPHY
BLOOD
BODY
BODY FLUIDS
CALCIUM
DIAGNOSTIC TECHNIQUES
DISEASES
ELEMENTS
ENDOCRINE GLANDS
ESTERS
GLANDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LUNGS
MATERIALS
MEDICINE
METALS
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
ORGANS
PARATHYROID GLANDS
PATIENTS
PHOSPHONIC ACID ESTERS
RADIOISOTOPES
RADIOLOGY
RESPIRATORY SYSTEM
TECHNETIUM 99
TECHNETIUM ISOTOPES
UPTAKE
YEARS LIVING RADIOISOTOPES