Early glottic carcinoma: factors affecting radiation failure, results of treatment and sequelae

Journal Article · Fri Jun 01 04:00:00 EDT 1979 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(79)90065-8· OSTI ID:5793193

E D, Mills E

The radiotherapy falure rate of 101 patients with T1, T2 and T3 glottic squamous carcinoma was analyzed with respect to age, race, sex, pathological grade, radiation dose, radiation treatment-field arrangement, and surgical salvage rate. All patients who received telecobalt therapy for glottic disease were included. The group comprised 25% of 400 intrinsic squamous carcinomas of the larynx, treated in the Radiotherapy Department, Groote Schuur Hospital, from 1968 to 1975. Ninety-six patients were assessable. In all, disease was Stage N.0 at presentation; 33 failed locally, 6% developed nodal recurrence, 7% developed second primaries, 2% had distant metastases and 8% died of unrelated causes. Radiation sequelae and the importance of pathologic grade are discussed.

• Research Organization: Groote Schuur Hospital, Cape Town, South Africa
• OSTI ID: 5793193
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 5:6; ISSN IOBPD
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
CARCINOMAS
CENTRAL NERVOUS SYSTEM
COBALT 60
COBALT ISOTOPES
DELAYED RADIATION EFFECTS
DISEASES
DOSES
EARLY RADIATION EFFECTS
EDEMA
ELECTROMAGNETIC RADIATION
EXTERNAL IRRADIATION
FRACTIONATED IRRADIATION
GAMMA RADIATION
INFLAMMATION
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LARYNX
MEDICINE
MINUTES LIVING RADIOISOTOPES
MUCOUS MEMBRANES
NEOPLASMS
NERVOUS SYSTEM
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
PARTIAL BODY IRRADIATION
PATHOLOGICAL CHANGES
PATIENTS
RADIATION DOSES
RADIATION EFFECTS
RADIATION SYNDROME
RADIATIONS
RADIOINDUCTION
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
RESPIRATORY SYSTEM
SIDE EFFECTS
SPINAL CORD
SYMPTOMS
THERAPY
YEARS LIVING RADIOISOTOPES