The relationship of drinking water chlorination and serum lipids in human populations
This research tests hypotheses concerning the relationship between drinking water characteristics and the cardiovascular disease risk factors blood pressure and serum lipids, as well as thyroid function. The study used a cross-sectional survey design to examine the characteristics of the cardiovascular disease risk factors in residents of forty-six small communities in central Wisconsin. Twenty of the communities chlorinated the water supply, and twenty-six did not. Within each of the chlorination groups, approximately half the communities had hard water and the other half had soft drinking water. This report examines the relationship of chlorination to serum lipid levels in the forty-six communities. Serum cholesterol levels were significantly higher in chlorinated communities for females. Levels of serum cholesterol were also higher in chlorinated communities for males, but the difference was not as great, nor was it statistically significant. LDL levels were higher in chlorinated communities, but did not reach statistical significance for either sex. Levels of high-density lipoprotein cholesterol were related to calcium level of the drinking water within the hardness categories, but only in the chlorinated communities. Thus chlorine and calcium level in the drinking water may interact in some way which affects levels of HDL cholesterol. 24 refs., 1 fig., 2 tabs.
- Research Organization:
- Oak Ridge National Lab., TN (USA); Environmental Protection Agency, Cincinnati, OH (USA)
- DOE Contract Number:
- AC05-84OR21400
- OSTI ID:
- 5784847
- Report Number(s):
- CONF-870524-1; ON: DE87013873
- Resource Relation:
- Conference: 6. conference on water chlorination: environmental impact and health effects, Oak Ridge, TN, USA, 3 May 1987; Other Information: Paper copy only, copy does not permit microfiche production
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
99 GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE
BLOOD PRESSURE
RESPONSE MODIFYING FACTORS
CARDIOVASCULAR DISEASES
DRINKING WATER
CHLORINATION
MONOCARBOXYLIC ACIDS
THYROID
CALCIUM COMPOUNDS
RISK ASSESSMENT
WATER CHEMISTRY
WISCONSIN
ALKALINE EARTH METAL COMPOUNDS
BODY
CARBOXYLIC ACIDS
CHEMICAL REACTIONS
CHEMISTRY
DISEASES
ENDOCRINE GLANDS
FEDERAL REGION V
GLANDS
HALOGENATION
HYDROGEN COMPOUNDS
NORTH AMERICA
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
OXYGEN COMPOUNDS
USA
WATER
550600* - Medicine
550900 - Pathology
570000 - Health & Safety