Arenaviruses. Genes, proteins, and expression
This book provides a discussion of current knowledge on Arenaviruses. These viruses are the cause of major health problems, such as Lassa fever and Junin virus disease, and have been the Rosetta stone on which many of the major concepts in viral pathogenesis and immunobiology have been built. For example, study of lymphocytic choriomeningitis naturally and experimentally induced infection in the normal mouse host presented the scientific community with the first and definitive work on the following topics: virus induced immune response disease, immunologic tolerance, virus induced immune complex disease, presence and generation of cytotoxic T cells in vitro and in vivo, H-2 restriction and dual recognition phenomena, and viral disease induced by altering physiologic or differential functions of a cell without causing alterations of house keeping or vital functions, i.e. pathology in the absence of cell or tissue lysis.
- OSTI ID:
- 5783335
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
ANIMAL CELLS
VIRAL DISEASES
LYMPHOCYTES
BEHAVIOR
CLASSIFICATION
MENINGES
INFLAMMATION
PROTEINS
STRUCTURE-ACTIVITY RELATIONSHIPS
IMMUNOLOGY
PATHOGENESIS
VIRULENCE
MOLECULAR BIOLOGY
VIRUSES
GENETIC MAPPING
GENOME MUTATIONS
IMMUNE REACTIONS
CELL KILLING
GENES
IN VITRO
IN VIVO
RNA
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CONNECTIVE TISSUE CELLS
DISEASES
INFECTIOUS DISEASES
LEUKOCYTES
MAPPING
MATERIALS
MEMBRANES
MICROORGANISMS
MUTATIONS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
PARASITES
PATHOLOGICAL CHANGES
SOMATIC CELLS
SYMPTOMS
550400* - Genetics
550900 - Pathology